Independent analytical testing. Results apply only to the sample received, for research use only.

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Matrix effect

Seen on limitation statements.

Definition

The influence everything other than the analyte has on the measurement: suppressing ionisation, interfering with detection, or reducing recovery. It is the reason a finished formulation is a much harder submission than raw powder.

Related terms

Ion suppression
Reduction of an analyte signal caused by co-eluting material competing for charge during ionisation.
Recovery
The proportion of a known added amount that the whole method actually finds.

About quantitation and content

How much is actually there, on what basis, and against what standard.

Peptide contentLabel claimPeptide base versus gross saltCounter-ionResidual moistureReference standardCalibration curveLinearityWorking rangeLimit of detectionLimit of quantitationReporting limitMeasurement uncertainty

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