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Baseline

Seen on chromatograms.

Definition

The detector response with no analyte eluting. A stable baseline is what makes integration limits meaningful; drift or noise large relative to a small peak is a reason a run is repeated rather than reported.

Related terms

Integration
The process of defining where each peak starts and ends on the baseline and calculating the area between.
Signal-to-noise ratio
The height of an analyte response relative to the baseline noise around it.

About chromatography

Separation, detection, and the figures that come out of a chromatographic run.

Reversed-phase chromatographyGradientRetention timeArea purityResolutionCo-elutionTailing factorTheoretical platesDetection wavelengthChromophoreIon pairingOrthogonal method

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