Independent analytical testing. Results apply only to the sample received, for research use only.

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Resolution

Seen on system suitability records.

Definition

A numerical measure of how completely two adjacent peaks are separated, combining their spacing and their widths. A method requirement for resolution between the principal peak and its nearest neighbour is what makes a purity figure defensible.

Related terms

Co-elution
Two or more components leaving the column at the same time and integrating as a single peak.
System suitability
The set of checks a run must pass before any of its results are reportable: blanks, replicate standards, resolution, symmetry, calibration performance, recovery.

About chromatography

Separation, detection, and the figures that come out of a chromatographic run.

Reversed-phase chromatographyGradientRetention timeArea purityIntegrationBaselineTailing factorTheoretical platesDetection wavelengthChromophoreIon pairingOrthogonal methodSignal-to-noise ratio

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