Definition
A second method that separates or detects on a different physical principle from the first, so that what the first method could not distinguish, the second can. Orthogonal work is how a co-elution suspicion is resolved.
Related terms
About chromatography
Separation, detection, and the figures that come out of a chromatographic run.
Reversed-phase chromatographyGradientRetention timeArea purityIntegrationBaselineResolutionTailing factorTheoretical platesDetection wavelengthChromophoreIon pairingSignal-to-noise ratio