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Tailing factor

Seen on system suitability records.

Definition

A measure of peak asymmetry. Excessive tailing distorts integration and usually signals a column, mobile-phase, or sample-loading problem, so it is one of the checks a run has to pass before its results are reportable.

Related terms

System suitability
The set of checks a run must pass before any of its results are reportable: blanks, replicate standards, resolution, symmetry, calibration performance, recovery.
Ion pairing
The use of a mobile-phase additive that pairs with charged sites on the analyte to improve retention and peak shape.

About chromatography

Separation, detection, and the figures that come out of a chromatographic run.

Reversed-phase chromatographyGradientRetention timeArea purityIntegrationBaselineResolutionCo-elutionTheoretical platesDetection wavelengthChromophoreOrthogonal methodSignal-to-noise ratio

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